Never before have prospective vaccines for a pathogen entered final-stage clinical trials as rapidly as candidates for Covid-19. Hopes and stakes are incredibly high.
For an excellent update on the most technologically enabled race for a vaccine in human history read ‘A huge experiment’: How the world made so much progress on a COVID-19 vaccine so fast. Still, even best-case scenarios require realism:
A vaccine that prevents even 50% of infections would be a massive lifeline. But experts worry there’s a disconnect between a public expecting vaccines to instantly reset their lives and what the first vaccines may actually allow. Successful vaccines will likely be restricted to frontline workers and vulnerable populations at first. It could take some time for enough vaccine to be made for everyone who wants a shot. Some vaccines might require two doses to confer protection.
“It might not be some magic bullet that’s going to stop the pandemic in its tracks, and people need to be prepared for that possibility,” said Columbia University virologist Angela Rasmussen about the first vaccines that reach people. “I really hate the term vaccine race. Because that implies there’s going to be a medal ceremony, and the pandemic is over.”