The future of medicine

Must listen discussion. If we learn and adapt, the future is bright.

Lee Hood (world-renowned biologist) and Nathan Price (professor) are the authors of The Age of Scientific Wellness: Why the Future of Medicine Is Personalized, Predictive, Data-Rich, and in Your Hands. Lee and Nathan join the Armchair Expert to discuss how artificial intelligence is changing the medical industry, how infectious disease has impacted our world, and the effectiveness of prescriptions. Lee, Nathan, and Dax talk about the ways treating chronic disease has become a business, what systems biology is, and the advances in preventing Alzheimer’s. Lee and Nathan explain digital twins and how they’ll change medicine, the future of wellness and prevention, and the differences between your biological and chronological age. Here is a direct audio link.

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Bank of Canada strikes again

Yesterday, concerned about lagging inflation readings and renewed froth in Canadian housing markets, the Bank of Canada came off its pause since January and announced yet another 25 bps hike. Now at 4.75%, the dramatic 450bps of rate increases since March 2022 are shown below from the BOC website, all in addition to quantitative tightening (liquidity withdrawal via balance sheet reduction). Fed futures are now pricing a 100% chance of another 25 bps in 2023. Bonds and dividend-paying equities have sold off in response. Before banking on the BOC’s present prediction for a 5% base rate by the end of 2023, it’s worth remembering that in 2021 they predicted it would be .75%. So, pinches of salt apply.

Lest anyone forget, changes in monetary policy move through the economy at a lag of 12 to 18 months, suggesting that the tightening since March 2022 has only started to be felt.

Floating-rate loans and variable-rate mortgages move with central bank base rates. Fixed-rate loans and mortgages move with Treasury bond yields as loans come up for renewal. The chart below from Ratehub (since 2006) shows the leap in Canadian variable and new fixed-term mortgages since 2021–now the highest in 17 years.
This matters a ton: A third of Canadian mortgages are variable rate (have already seen a 50% increase in interest costs year-over-year), and the other two-thirds will be renewing between now and 2026 with a 20 to 40% increase in payments (BOC data). Already, in April, the year-over-year drop in the price of Canadian homes that sold was 8.5% (shown below since 2000, courtesy of Charlie Bilello)–the largest decline since 1981. Given the multi-month time lags,  monetary policy will continue to be a drag on consumer spending, the housing market and the economy long after the central banks stop hiking and return to loosening efforts once more.

As unemployment (lagging labour indicator) starts to leap, policymakers will reverse course. But as in past recessions and bear markets, that will be too late to avoid job losses, bankruptcies and imploding asset markets.

After leaving monetary conditions recklessly loose for years, central banks are trying to restore their credibility through tough love. What the BOC did yesterday will make the financial and economic downside deeper for longer in Canada. On the upside, painful as it will be for many, the flush-out is needed and will undoubtedly produce highly valuable investment opportunities in the process.

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Recession is the policy goal and it will be achieved

A deflationary recession is the goal of central bank policies today. They’re determined to get there, and they will succeed. Make no mistake. Eric’s update is worthwhile. Eyes on the prize. (You can fast-forward through the channel’s crypto commercials).

On today’s episode of On The Margin, Eric Basmajian Founder of EPB Research joins the show for a discussion on the business cycle slowdown that suggests a “recession is imminent”. With Eric’s research following leading, cyclical and lagging indicators, he manages to keep a pulse on the current economic environment and its ultimate impact on markets. Here is a direct video link.

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